Cherqaoui Driss - Profil du chercheur

Informations du chercheur

Nom complet

Cherqaoui Driss

Grade

PES

Spécialité

Chimie organique

Thématique de recherche

Synthèse organique et modélisation moléculaire

Laboratoire

Laboratoire de Chimie Moléculaire

Établissement

Faculté des Sciences Semlalia Marrakech

Ouvrages (0 au total)

Aucun ouvrage disponible.

Projets (2 au total)

Approches in silico, hémi-synthèse et évaluations biologiques pour le développement de nouveaux produits anticancéreux ciblant les MMPs

Type: Non spécifié

Début: 01/07/2025

Fin: 31/07/2027

Organisme financeur:

AAP « Promotion des Projets Interdisciplinaires » _ UCA

Modélisation moléculaire : Contribution à la conception d’inhibiteurs du VIH

Type: Non spécifié

Début: 01/01/2017

Fin: 30/12/2018

Organisme financeur:

Agence Universitaire de la Francophonie” and the Scientific Research Fund of Bulgaria. under project DNTS/FrPh01/1.

Publications (36 au total)

Anti-proliferative and antidiabetic potential of vanillin-linked isoxazole hybrids targeting α-glucosidase: Synthesis, in vitro and in silico evaluation

Auteur: Mohamed Adardour, Nouhaila Ait Lahcen, Abdoussadeq Ouamnina, Marouane Ait Lahcen, Ismail Hdoufane, Mohammed M. Alanazi, Elena Zaballos-García, Imane Elateri, Driss Cherqaoui, Abdesselam Baouid

Revue: Journal of Molecular Structure

Année: 2026

DOI: 10.1016/j.molstruc.2025.144610

One-pot synthesis via [3+2] cycloaddition reaction, structural analysis, and computational insights of obtained oxadiazole-benzodiazepine derivatives as potential kinase inhibitors

Auteur: Samir Hmaimou, Nouhaila Ait Lahcen, Marouane Ait Lahcen, Ismail Hdoufane, Mohamed Adardour, Paola Vitale, Maria Grazia Perrone, Driss Cherqaoui, Mohamed Maatallah, Abdesselam Baouid

Revue: Journal of Molecular Structure

Année: 2025

DOI: 10.1016/j.molstruc.2025.143117

1,2,4-triazolo-1,5-benzodiazepine diastereoisomers: Synthesis, structural elucidation and computational insights for anti-ebola activity

Auteur: Marouane Ait Lahcen, Nouhaila Ait Lahcen, Saad Zekri, Ashwag S. Alanazi, Samir Hmaimou, Mohammed M. Alanazi, Mohamed Adardour, Ismail Hdoufane, Karim Chkirate, Joel T. Mague, Driss Cherqaoui, Abdesselam Baouid

Revue: Journal of Molecular Structure

Année: 2025

DOI: 10.1016/j.molstruc.2025.142736

Design, synthesis and molecular modeling of new Pyrazolyl-Benzimidazolone hybrids targeting breast Cancer

Auteur: Mohamed Adardour, Al-Hassan M. Mustafa, Mehdi Oubahmane, Marouane Ait Lahcen, Emad M. Seif, Manal Abdel Fattah Ezzat, Elena Zaballos-García, Joel T. Mague, Ismail Hdoufane, Driss Cherqaoui, Oliver H. Krämer, Wolfgang Sippl, Hany S. Ibrahim, Abdesselam Baouid

Revue: Bioorganic Chemistry

Année: 2025

DOI: 10.1016/j.bioorg.2025.108269

Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations

Auteur: Ismail Hdoufane, Mehdi Oubahmane, Youssef Habibi, Christelle Delaite, Mohammed M. Alanazi, Driss Cherqaoui

Revue: Scientific Reports

Année: 2025

DOI: 10.1038/s41598-025-86961-5

Efficient Synthesis, Structural Characterization, DFT Analysis, and Molecular Dynamics of a Benzimidazolone Derivative as an Antidiabetic Inhibitor

Auteur: Mohamed Adardour, Nouhaila Ait Lahcen, Laura Chelazzi, Samuele Ciattini, Mohamed Maatallah, Driss Cherqaoui, Abdesselam Baouid

Revue: ChemistrySelect

Année: 2025

DOI: 10.1002/slct.202504602

Deciphering the cytotoxic and antioxidant potential of 3,5-disubstituted isoxazole-linked benzimidazolone derivatives

Auteur: Mohamed Adardour, Soufiane Drioua, Marouane Ait Lahcen, Ismail Hdoufane, Elena Zaballos-García, Mohammed M. Alanazi, Anass Doukkali, Karim Chkirate, Driss Cherqaoui, Joel T. Mague, Abdesselam Baouid

Revue: Journal of Molecular Structure

Année: 2025

DOI: 10.1016/j.molstruc.2024.139683

Computational design of potent dimeric phenylthiazole NS5A inhibitors for hepatitis C virus

Auteur: Wissal Liman, Mehdi Oubahmane, Nouhaila Ait Lahcen, Ismail Hdoufane, Driss Cherqaoui, Rachid Daoud, Achraf El Allali

Revue: Scientific Reports

Année: 2024

DOI: 10.1038/s41598-024-80082-1

New Schiff bases and their vanadium complexes: Synthesis, characterization, and biological assessment for antibacterial and antiviral action

Auteur: Khadija Khaldoune, Ali Hasnaoui, Meryem Rafya, Meriem Es‐sakhi, Fatiha Benkhalti, Ismail Hdoufane, Joel T. Mague, Johan Neyts, Dirk Jochmans, Driss Cherqaoui, Larbi el Firdoussi, Naima Fdil, Hassan Bihi Lazrek, Mustapha Ait Ali

Revue: Applied Organometallic Chemistry

Année: 2024

DOI: 10.1002/aoc.7534

1 2 3 Suivant »

Communications (61 au total)

Identification of novel TMPRSS4 inhibitors via homology modeling, molecular docking and molecular dynamics

Manifestation: 33rd edition of the International Congress of “Apollonia” University of Iasi

Date: 2023-03-02

Organisation: Apollonia University of Iasi, Iasi, Roumanie

8. In silico studies toward the identification of potential glycoprotein inhibitors as anti-Ebola agents

Manifestation: 33rd edition of the International Congress of “Apollonia” University of Iasi

Date: 2023-03-02

Organisation: Apollonia University of Iasi, Iasi, Roumanie

Identification of new potential HCV inhibitors

Manifestation: International bioinformatics conference (IBC 2022):Drug Design

Date: 2022-10-08

Organisation: Tanger, Maroc

In Silico approaches for the design of HCV inhibitors

Manifestation: Science week talks

Date: 2022-05-31

Organisation: Université Mohammed VI Polytechnique, Ben Guérir, Morocco

In silico QSAR-based discovery and molecular docking of novel inhibitors of the SARS-COV-2 main protease (Mpro)

Manifestation: 32nd edition of the international congress of Apollonia University "Preparing the Future by Promoting Excellence"

Date: 2022-03-02

Organisation: Iasi, Romania

QSAR Study of NS5A Inhibitors against Hepatitis C Virus using the Monte Carlo Optimization and the Genetic Algorithm Multiple Linear Regression(GA-MLR) Models

Manifestation: 6th International Conference on Computational Science and Technology 2021-ICCST

Date: 2021-10-31

Organisation: Faculty of Pharmacy, Chiang Mai University, Thailand

In silico identification of potent α-ketoamide inhibitors targeting the main protease of the SARS-CoV-2

Manifestation: 6th International Conference on Computation For Sciences and Technology

Date: 2021-10-30

Organisation: Thailand

Combined singular value decomposition and linear regression methods in QSAR modelling: a case study for predicting HIV-1 and HCV biological activities

Manifestation: International Congress of &bdquo;Apollonia” University from Iași By promoting excellence, we prepare the future Edition XXXI

Date: 2021-03-01

Organisation: IAȘI, ROMANIA

Impact assessment of singular value decomposition linear regression model on QSAR modelling: A case study for predicting HIV-1 and HCV biological activities.

Manifestation: Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2019)

Date: 2019-06-23

Organisation: Ioannina, Greece.

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Thèses (3 au total)

In Silico Drug Design of Potent SARS-CoV-2 Inhibitors

Auteur: Mehdi OUBAHMANE

Directeur: Cherqaoui Driss

Soutenance: 2023

Molecular Modeling: QSAR Studies on Reverse Transcriptase and Gp120 HIV-1 and NS4B HCV Inhibitors

Auteur: HDOUFANE Ismail

Directeur: Cherqaoui Driss

Soutenance: 2021

Targeting Protein Degradation as a Potential and Emerging Therapeutic Approach in Cancer Drug Discovery: Combinatorial In Silico Modeling to Explore the Covalent & Non-covalent Inhibition of Nedd4-1 E3 Ubiquitin Ligase

Auteur: BJIJ Imane

Directeur: Cherqaoui Driss

Soutenance: 2019

Informations du chercheur

Nom complet

Grade

Spécialité

Thématique de recherche

Laboratoire

Établissement

Ouvrages (0 au total)

Projets (2 au total)

Approches in silico, hémi-synthèse et évaluations biologiques pour le développement de nouveaux produits anticancéreux ciblant les MMPs

Mod&eacute;lisation mol&eacute;culaire : Contribution &agrave; la conception d&rsquo;inhibiteurs du VIH

Publications (36 au total)

Anti-proliferative and antidiabetic potential of vanillin-linked isoxazole hybrids targeting α-glucosidase: Synthesis, in vitro and in silico evaluation

One-pot synthesis via [3+2] cycloaddition reaction, structural analysis, and computational insights of obtained oxadiazole-benzodiazepine derivatives as potential kinase inhibitors

1,2,4-triazolo-1,5-benzodiazepine diastereoisomers: Synthesis, structural elucidation and computational insights for anti-ebola activity

Design, synthesis and molecular modeling of new Pyrazolyl-Benzimidazolone hybrids targeting breast Cancer

Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations

Efficient Synthesis, Structural Characterization, DFT Analysis, and Molecular Dynamics of a Benzimidazolone Derivative as an Antidiabetic Inhibitor

Deciphering the cytotoxic and antioxidant potential of 3,5-disubstituted isoxazole-linked benzimidazolone derivatives

Computational design of potent dimeric phenylthiazole NS5A inhibitors for hepatitis C virus

New Schiff bases and their vanadium complexes: Synthesis, characterization, and biological assessment for antibacterial and antiviral action

Communications (61 au total)

Identification of novel TMPRSS4 inhibitors via homology modeling, molecular docking and molecular dynamics

8. In silico studies toward the identification of potential glycoprotein inhibitors as anti-Ebola agents

Identification of new potential HCV inhibitors

In Silico approaches for the design of HCV inhibitors

In silico QSAR-based discovery and molecular docking of novel inhibitors of the SARS-COV-2 main protease (Mpro)

QSAR Study of NS5A Inhibitors against Hepatitis C Virus using the Monte Carlo Optimization and the Genetic Algorithm Multiple Linear Regression(GA-MLR) Models

In silico identification of potent α-ketoamide inhibitors targeting the main protease of the SARS-CoV-2

Combined singular value decomposition and linear regression methods in QSAR modelling: a case study for predicting HIV-1 and HCV biological activities

Impact assessment of singular value decomposition linear regression model on QSAR modelling: A case study for predicting HIV-1 and HCV biological activities.

Thèses (3 au total)

In Silico Drug Design of Potent SARS-CoV-2 Inhibitors

Molecular Modeling: QSAR Studies on Reverse Transcriptase and Gp120 HIV-1 and NS4B HCV Inhibitors

Targeting Protein Degradation as a Potential and Emerging Therapeutic Approach in Cancer Drug Discovery: Combinatorial In Silico Modeling to Explore the Covalent &amp; Non-covalent Inhibition of Nedd4-1 E3 Ubiquitin Ligase

Modélisation moléculaire : Contribution à la conception d’inhibiteurs du VIH

Targeting Protein Degradation as a Potential and Emerging Therapeutic Approach in Cancer Drug Discovery: Combinatorial In Silico Modeling to Explore the Covalent & Non-covalent Inhibition of Nedd4-1 E3 Ubiquitin Ligase